The Next Frontier Is Inner Space

What Neuroscience Reveals About Consciousness, Meditation, and Human Flourishing

An Evening Conversation with Jay Sanguinetti

Moderator: Sanjay Manchanda

For thousands of years, contemplative traditions have explored the nature of mind through meditation, inquiry, and direct experience. Today, neuroscience is beginning to investigate many of these same questions through brain imaging, neurofeedback, and emerging technologies that offer new ways of understanding attention, awareness, and human potential.

Yet profound questions remain.

Can consciousness ever be fully explained by science? Can technology genuinely support inner transformation, or are there dimensions of wisdom that lie beyond measurement? As artificial intelligence and neurotechnology continue to reshape our world, what does it mean to cultivate a sound mind, a compassionate heart, and a meaningful life?

Join neuroscientist Jay Sanguinetti for a thought-provoking conversation exploring the intersection of neuroscience, contemplative practice, and the future of human flourishing.

Together, we will examine how ancient wisdom and modern science may illuminate one another—and what this convergence might mean for the next chapter of human development.

Why This Conversation Matters

As we stand at the threshold of unprecedented technological change, perhaps the most important frontier is not outer space, but inner space. Understanding the nature of mind may prove to be one of the defining challenges—and opportunities—of our century.

Berkeley Circle
A gathering place for conversations at the intersection of wisdom, science, innovation, and what it means to be fully human.

Bios:

About Jay Sanguinetti (https://www.jaysanguinetti.com/)

Jay Sanguinetti is a neuroscientist, entrepreneur, contemplative researcher, and environmentalist. He is the CEO and co-founder of Sanmai, a Public Benefit Corporation which is creating a clinical ultrasound neuromodulation platform guided by individualized beam modeling for neurological and psychiatric disorders. The Lotus transcranial ultrasound system delivers precise deep-brain stimulation without surgery. The goal is to open a new path for low-intensity ultrasound neurotherapeutics, starting with Parkinson's disease. Based in Sunnyvale, California, the company is actively pursuing FDA clearance.

He co-directs the Science Enhanced Mindful Awareness (SEMA) Lab at the University of Arizona with meditation teacher and scholar Shinzen Young and Distinguished Professor John J.B. Allen. The lab studies the neural basis of mindfulness and turns that science into tools that help more people experience the benefits of meditation. SEMA has pioneered causal brain mapping in the young field of contemplative neuroscience, and was among the first to combine low-intensity neuromodulation with mindfulness training to study how capacities like equanimity may underlie the benefits of contemplative practice.

Sanguinetti trained as a psychophysiologist, with expertise spanning EEG, fMRI, and eyetracking. He was an early researcher of transcranial ultrasound neuromodulation and has published widely across visual perception, emotion, mindfulness meditation, and the neural basis of depression, anxiety, and Parkinson's disease, working with collaborators that include Google, the BrainMind Institute, and research labs worldwide. He earned his Ph.D. from the University of Arizona and has contributed to consciousness science through his work with the Center for Consciousness Studies. Long-term, he is building human-centered technologies that help people live better lives.

About Sanjay Manchanda (https://neuromatrix.health/pages/about-neuromatrix)

Sanjay Manchanda PhD has been a psychotherapist and wisdom teacher for over thirty years. Prior to that he was an Electrical Engineer and Computer Scientist. He left his job as a Computer Science professor in response to an inner spiritual calling.

Following a major spiritual awakening, he trained in various spiritual mystical traditions, particularly different forms of Buddhism and Hinduism as well as in various forms of body and mind therapeutic work. He has a highly integrated approach to teaching and working with people that includes the body, mind and spirit. He teaches courses and runs an ongoing group on psycho-spiritual integration. His teaching is a confluence of the wisdom streams of Eastern and Western knowledge. He is the Director of Psychedelic Studies at the California Institute of Human Science in San Diego. He also teaches for the California Institute of Integral Studies in San Francisco, and the Fundamental Well-being Foundation.

Twenty years ago, he became interested in biofeedback, particularly neurofeedback for helping people access different mind-body states and improve mood and attention. Since then, he has also specialized in various forms of brain stimulation using low levels of energy transfer to the brain for accessing useful states of mind (for example, tDCS and PEMF, and photo-biomodulation).

He is the CEO of Firelight Technologies, a photobiomodulation company that sells the Neuromatrix, an infrared light device that promotes brain recovery, and peak cognitive performance. They also specialize in creating devices for accessing deep meditation states. They have an ambitious research and product development program that aims to improve access to meditation for the wider population using technology as a catalyst.

In his private practice and coaching, he assists people with non-dual awakening, shadow work, psycho-spiritual integration, meditation, improved performance and life flow, and in dealing with brain injuries and cognitive issues. The overall goal of his work is to support human flourishing and the evolution of human consciousness using a variety of approaches and tools.

Berkeley Circle #3: The Next Frontier Is Inner Space What Neuroscience Reveals About Consciousness, Meditation, and Human Flourishing